Steroid hormone receptors: a survey.
W I Mainwaring
Literature on the mechanism of action of steroid hormones and their receptors is reviewed. A general model for the mechanism of action of steroid hormones is presented and its limitations are discussed. The entry into and release from cells of steroid hormones, steroid antagonists, aspects of steroid metabolism, conventional approaches to the purification of steroid-receptor complexes and affinity chromatography, and the specificity of cytoplasmic and nuclear steroid receptors and discussed. Further research is required to explain satisfactorily the tissue specificity of hormonal responses and the natu re of the nuclear acceptor.
KEYWORDS: Androgens/Biology/Endocrine System/Estradiol/Estrogens/Hormone Antagonists/Hormone Receptors/Hormones/Literature Review/Membrane Proteins/Metabolic Effects/Physiology/Progestational Hormones/Progesterone/Stanolone/Steroid Metabolic Effects/Testosterone/
| Humans or Animals | Animals |
| Type of Article | Review; Journal Article |
| Periodical |
Vitamins and hormones
| Publication Date |
1975
|
| Volume |
33
| Issue |
|
| Start Page |
| End Page |
45
|
| Vernacular Title |
| Abstract Copyright Info |
|
| ISSN |
| ISSN Type |
|
| NLM ID |
0413601
| PubMed ID |
180674
|