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GST Primary GST Primary Best Strategies for Health Care Quality Im... Best Strategies for Health Care Quality Improvement - Diabetes Quality Improvement Strategies for Antibio... Kathryn McDonald, Stanford-UCSF Evidence-b... Systematic review assessing the effect of ... Quality Improvement Strategies for Antibiotics Management Kathryn McDonald, Stanford-UCSF Evidence-based Practice Center, 117 Encina Commons, Stanford, CA 94305-6019, Kathy.mcdonald@stanford.edu Systematic review assessing the effect of quality improvement strategies on appropriate prescribing of antibiotics and appropriate choice of antibiotics. Adherence Adherence Assistive Devices Assistive Devices Childhood Burn Hanson MacMillan Childhood Burn Hanson MacMillan CLSA_9 CLSA_9 Cyberabuse Cyberabuse Cognitive Behavioural Therapy for Violent ... This review included randomized trials abo... Cognitive Behavioural Therapy for Violent Men who Batter Their Partners This review included randomized trials about the effects of cognitive behavioral therapy on domestic violence. The intervention included programs based on the Duluth Model. The violence had to be committed by a male toward his female partner. The violence also had to be physical. The primary outcomes were new arrests and convictions, and new reports of violence. CABG vs PCI CABG vs PCI Quality Improvement Strategies for Prevent... Quality Improvement Strategies for Preventing Nosocomial Infections (Created 17-Feb-06) Quality Improvement Strategies for Asthma ... Quality Improvement Strategies for Asthma Control Erectile Dysfunction (Created 30-Jan-06) Erectile Dysfunction (Created 30-Jan-06) Inequality - Smoking Cessation to Reduce S... This review was the first part of a projec... Inequality - Smoking Cessation to Reduce Socio-Economic Differences This review was the first part of a project about inequality. It included randomized trials about the effect of smoking cessation interventions on reducing socio-economic differences. The studies had to report data either on persons with low socio-economic groups status or, preferably, on both low and high socio-economic groups. Diet and Physical Activity to Reduce Socio... This review was the second part in a proje... Diet and Physical Activity to Reduce Socio-Economic Differences This review was the second part in a project about inequality. It included randomized trials about the effect of interventions on reducing socio-economic differences in diet and physical activity. The studies had to report data either on persons with low socio-economic groups status or, preferably, on both low and high socio-economic groups. Workfare The data in SRS are not identical to the d... Workfare The data in SRS are not identical to the data in the published report. We used SRS only for an updated search. The review included randomized trials about the effect of welfare-to-work programs. Participants were welfare recipients. There were basically two types of programs. The educational type tried to build knowledge and skills in order to help the welfare recipients acquire jobs that could support them economically. The "work first" approach was more aimed at getting the participants quickly into a job. Exercise interventions for the management ... The objective of this systematic review wa... Exercise interventions for the management of frailty The objective of this systematic review was to examine the effectiveness of current exercise interventions on the management of frailty. A comprehensive search of Medline, Embase, Psycinfo, Cinahl, Scopus, Ageline, Eric, and SportDiscus databases was conducted and produced 1808 citations. So far we have completed 2 levels of “title and abstract” screening and we ended up with 262 articles. We have just started the full text screening. Eligibility criteria included original studies whose participants were identified as frail or prefrail with specific criteria and in which structured physical activity was included as at least one component of the intervention. Create a free account, build a dictionary with saved terms to re-use later! Public Domestic Violence - Using Cognitive Behavior Therapy Smoking Cessation to Reduce Socio-Economic Differences Diet and Physical Activity to Reduce Socio-Economic Differences Workfare Exercise Interventions for the Management of Frailty Search     Simple Advanced Refine (4 coded questions)  Any of these:   Exact Phrase: All of these: None of these: Author: Periodical: Projects: No restrictions   Libraries: Public   Select SRS Projects Show Saved Terms Select Library Show articles that do not have abstracts  Humans or Animals Humans Animals Ages All Infant: birth-23 months All Child: 0-18 years All Adult: 19+ years Newborn: birth-1 month Infant: 1-23 months Preschool Child: 2-5 years Child: 6-12 years Adolescent: 13-18 years Adult: 19-44 years Middle Aged: 45-64 years Middle Aged + Aged: 45+ years Aged: 65+ years 80 and over: 80+ years Undetermined Type of Article Clinical Trial Editorial Letter Meta-Analysis Practice Guideline Randomized Controlled Trial Review Addresses Bibliography Biography Case Reports Classical Article Clinical Conference Clinical Trial, Phase I Clinical Trial, Phase II Clinical Trial, Phase III Clinical Trial, Phase IV Comment Comparative Study Consensus Development Conference Consensus Development Conference, NIH Controlled Clinical Trial Corrected and Republished Article Dictionary Directory Duplicate Publication English Abstract Evaluation Studies Festschrift Government Publications Guideline Historical Article Interview In Vitro Journal Article Lectures Legal Cases Legislation Multicenter Study News Newspaper Article Overall Patient Education Handout Periodical Index Published Erratum Retracted Publication Research Support, N.I.H., Extramural Research Support, N.I.H., Intramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. 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Retraction of Publication Scientific Integrity Review Support of Research Technical Report Twin Study Validation Studies Not a Primary Study or Review Unknown Primary Study Case Series Case Control Cohort Study Observational Study Qualitative Research CBA or ITS Registry Double Blind Controlled before after study Quasi-randomized trial Simple before after study Cluster-RCT Non-Randomized Study Report Book Book chapter Dissertation Conference procedings Secondary Research Not RCT Language English French German Italian Japanese Russian Spanish Afrikaans Albanian Unknown Arabic Armenian Azerbaijani Bosnian Bulgarian Catalan Chinese Croatian Czech Danish Dutch Esperanto Estonian Finnish Georgian Greek, Modern Hebrew Hindi Hungarian Icelandic Indonesian Kinyarwanda Korean Latin Latvian Lithuanian Macedonian Malay Malayalam Maori Multiple Languages Norwegian Persian Polish Portuguese Pushto Romanian Sanskrit Scottish gaelic Serbian Slovak Slovenian Swedish Thai Turkish Ukrainian Vietnamese Not English Not French Results(1-25 of 2,764) Sort By: Publication Date Relevance Took: 1.373 seconds to search 17,750,454  Action: Copy Results to new Clipboard Build Search Link Page 1 of 111 1 2 3 4 > Last >> (2764 articles found) PAR evaluation of treated Class I extraction patients. Mar 2008 Karina Maria Salvatore Freitas,Daniel Salvatore Freitas,Fabrício Pinelli Valarelli,Marcos Roberto Freitas,Guilherme Janson OBJECTIVE: To evaluate treatment changes and quality of finishing occlusion in Class I patients treated with four premolar extractions. MATERIAL AND METHODS: Dental casts of 94 subjects (50 males and 44 females) were evaluated. Mean pretreatment age was 13.46 years, and mean treatment time was 2.09... ( view more ) years. The peer assessment rating (PAR) index was obtained from pretreatment and posttreatment dental casts. RESULTS: The mean pretreatment PAR index of 29.46 was reduced to 6.32 at posttreatment stage, achieving a reduction of 78.54% with treatment. There was correlation between the initial PAR and correction during treatment, that is, the more severe the malocclusion the greater the treatment changes. CONCLUSION: The cases evaluated showed a high-standard orthodontic finishing. ( view less ) View Full Abstract View Article Details View Coded Data Related Articles Facial height comparison in young white and black Brazilian subjects with normal occlusion. Jun 2007 Lívia Maria Andrade de Freitas,Arnaldo Pinzan,Guilherme Janson,Karina Maria Salvatore Freitas,Marcos Roberto de Freitas,José Fernando Castanha Henriques INTRODUCTION: In this study, we aimed to cephalometrically compare anterior and posterior facial heights in young white and black Brazilian subjects with normal occlusion and to verify sexual dimorphism. METHODS: The sample comprised the lateral cephalograms of untreated normal Brazilians, divided ... ( view more )into 2 groups. Group 1 included 74 white subjects (37 of each sex), with a mean age of 13.71 years (SD 0.84); group 2 included 56 black subjects (28 of each sex), with a mean age of 13.86 years (SD 0.92). The variables studied were obtained from various cephalometric analyses. Sexual dimorphism was investigated in the groups. Independent t tests were used for intergroup comparisons. RESULTS: The white subjects had significantly greater upper anterior facial height (UAFH) and proportion of UAFH to total anterior facial height (TAFH), and significantly smaller proportion of lower anterior facial height (LAFH) to TAFH than the black subjects. Black boys had significantly greater total posterior face height (TPFH) and UAFH and upper posterior face height (UPFH) and UPFH/TPFH proportion than black girls. Black girls had significantly greater LPFH/TPFH proportion than boys. White boys had significantly greater UPFH and UPFH/TPFH proportion than white girls. White girls had significantly greater LPFH/TPFH and facial height index values than boys. CONCLUSIONS: White subjects had larger UAFH, whereas black subjects had proportionally larger LAFH. Boys have a greater tendency for a vertical pattern than girls. ( view less ) View Full Abstract View Article Details   Related Articles Heart rate variability in 24-hour Holter recordings. Comparative study between short- and long-term time- and frequency-domain analyses. Jul 1994 O Costa,P Lago,A P Rocha,M J Carvalho,A Freitas,J Freitas,J Puig,A Brandão,F de Freitas Mean hourly parameters obtained from all beats (long series) were compared with those obtained from a sample of 512 beats extracted each hour (short series) in nine presumably normal subjects. For both the short and long series, the spectral components, very low frequency, (VLF), low frequency (LF)... ( view more ), and high frequency (HF), and time-domain indices (such as the Ewing statistic [PNN50] and RR standard deviation [SD-RR]), have been estimated. The spectral components LF and HF, estimated from the short and long series, were not significantly different, whereas significant differences were found between VLF, SD--RR, and PNN50. In both the short and long series, a strong correlation was found between LF and SD-RR and between HF and PNN50. The results suggest that, over a period of 24 hours, hourly LF and HF spectral components can be obtained using a single series of 512 beats every hour, with a great advantage over the evaluation of the mean hourly parameters. This method would be particularly useful in the study of circadian heart rate spectral analysis in Holter recordings with multiple artifacts or ectopic beats, and in general, when analysis of the entire 24-hour series is not feasible. ( view less ) View Full Abstract View Article Details View Coded Data Related Articles [Spectrum analysis of the variability of heart rate in athletes] Jan 1991 O Costa,J Freitas,J Puig,M J Carvalho,A Freitas,J Ramos,N Puga,I Lomba,P Fernandes,F de Freitas OBJECTIVES: Characterize power spectrum pattern of the heart rate variability and assessment of the relative contributions of sympathetic and parasympathetic cardiac nervous system control in athletes. STUDY DESIGN: Prospective study of athletes and sedentary healthy control group sex and age match... ( view more )ed. SUBJECT AND METHODS: 8 athletes, 3 female and 5 male, swimming (4), canoeing (2) and cycling (2), aged 17.4 +/- 3.6 years, and 8 sedentary healthy controls. ECG signals were recorded after a period of 15 minutes in supine rest with controlled breathing at 15 cycles/min. Signal acquisition was done at 300 samples/sec. From 512 consecutive heart beats, we calculated the average, the standard deviation, the maximum and the minimum values and the rate between the longest and the shortest R-R interval (E/I). We also calculated, after computing the fast Fourier transform, the total spectrum power, the low frequency component (LF, from 0.01 to 0.15 Hz) and the high frequency component (HF, greater than 0.15 Hz) and its ratio (LF/HF). RESULTS: The average R-R interval was 921 +/- 154.2 msecs and 673.2 +/- 98 msecs, the standard deviation was 72.5 and 29.4 msecs and the ratio E/I 1.63 +/- 0.14 and 1.28 +/- 0.08, respectively for athletes and control group. Differences between groups were significant (p less than 0.01) for all parameters, with higher variability in the athletes. Both spectral bands (LF and HF) and higher power in athletes (LF = 0.54 +/- 0.23 and HF = 0.76 +/- 0.14) than in the control group (LF = 0.14 +/- 0.10 and HF = 0.18 +/- 0.15) (p less than 0.001). There were no significant differences for LF/HF ratio, or normalized LF (LF%) or normalized HF (HF%) between groups. CONCLUSIONS: The present results indicates higher power of both spectral bands (LF and HF) and higher amplitude of the respective peaks in athletes when compared with healthy sedentary, with a clear predominance of the HF band in the total spectral power density, which suggest that the higher heart rate variability observed in athletes reveals the predominance of parasympathetic activity, without reduction of the sympathetic tone. ( view less ) View Full Abstract View Article Details View Coded Data Related Articles Neuroprotective actions of vitamin C related to decreased lipid peroxidation and increased catalase activity in adult rats after pilocarpine-induced seizures. Mar 2008 Lúcia F L Santos,Rizângela L M Freitas,Sarah M L Xavier,Gláucio B Saldanha,Rivelilson M Freitas In the present study, we examined the neuroprotective effects of vitamin C in adult rats after pilocarpine-induced seizures. Vitamin C is an exogenous antioxidant that can be used in treatment of seizures. It can alter oxidative stress and damage neuronal induced by seizures. Its antioxidant proper... ( view more )ties can be proved in epilepsy models, such as pilocarpine-induced seizures in adult rats. In order to investigate neuroprotective effects of vitamin C, adult male rats (2 months-old) were pretreated with vitamin C (VIT C 250 mg/kg, i.p.) 30 min before receiving pilocarpine (400 mg/kg, s.c., P400 group). The other three groups were treated with vitamin C (VIT C group) and saline 0.9 (control group) alone. The pretreatment with vitamin C increased the latency to first seizures and reduced mortality rate after pilocarpine-induced seizures. Pretreatment with vitamin C alone decrease lipid peroxidation levels when compared to pilocarpine group and P400+VIT C. In P400, P400+VIT C and VIT C groups were observed an increased hippocampal catalase activity when compared to control group. Our results can suggest that neuroprotective effects of vitamin C in adult rats can be the result of reduced lipid peroxidation levels and increase of catalase activity after seizures and status epilepticus induced by pilocarpine. ( view less ) View Full Abstract View Article Details View Coded Data Related Articles Mucoid degeneration of the anterior cruciate ligament: magnetic resonance imaging findings of an underdiagnosed entity. Feb 2008 J L Fernandes,S L Viana,J L F Mendonça,F M O Freitas,A S A Bezerra,G-A S Lima,V L Matos,N F Cunha,R R Martins,R M O Freitas Although imaging and clinical criteria are already established for the diagnosis of mucoid degeneration of the anterior cruciate ligament (ACL), many radiologists remain unaware of their existence. Once regarded as a rare occurrence, it has been recently suggested that its incidence is in fact very... ( view more ) much higher than previously thought, and that it is probably underdiagnosed or misdiagnosed as partial ruptures of the ACL or as cystic ganglia. In this review, the authors revisit the literature concerning this subject and present their personal experience with it, stressing the paramount importance of magnetic resonance imaging and correlation with clinical data for a correct diagnosis. ( view less ) View Full Abstract View Article Details View Coded Data Related Articles The "pressure pan" evolution of human erythrovirus B19 in the Amazon, Brazil. Dec 20, 2007 Ronaldo Barros de Freitas,Edison Luiz Durigon,Darleise de Souza Oliveira,Camila Malta Romano,Maria Rute Castro de Freitas,Alexandre da Costa Linhares,Fernando Lucas Melo,Lílian Walshkeller,Maria Luisa Barbosa,Egma M Mayta Huatuco,Edward C Holmes,Paolo Marinho de A Zanotto To understand the evolutionary dynamics of human parvovirus B19, we analyzed VP1 and VP2 gene sequences of B19 sampled from Belém (Amazon), the city of São Paulo, Brazil and globally. Our analysis revealed a strikingly different pattern of evolutionary change for those viral lineages introduced int... ( view more )o Belém, which exhibited a higher rate of nonsynonymous substitutions compared to those viruses sampled from other locations. We propose that difference this is due to the high prevalence of B19 in Belém (up to 85%) compared to other locations (prevalences of approximately 50%), which imposes a more intense selection pressure. Hence, those B19 lineages introduced into Belém experienced an elevated rate of amino acid change, driven by positive selection, in order to generate serial re-infections in a small web of transmission, which can be thought of as an evolutionary "pressure pan". ( view less ) View Full Abstract View Article Details View Coded Data Related Articles Transforming growth factor-beta 1 gene polymorphisms and expression in the blood of prostate cancer patients. Dec 2007 Paula Cristina Faria,Karla Saba,Adriana Freitas Neves,Elisangela Rosa Cordeiro,Karina Marangoni,Danielo Garcia Freitas,Luiz Ricardo Goulart The transforming growth factor beta 1 (TGF-beta1) is a multifunctional cytokine with several regulatory activities in tumor cells affecting growth, differentiation, and function. Alterations in gene expression, secretion, and regulation of TGF-beta1 may lead to a favorable environment for tumor dev... ( view more )elopment by angiogenesis stimulation and immune system suppression. We evaluated the influence of the TGFB1 polymorphisms by ARMS-PCR, Leu10Pro, and Arg25Pro, on prostate cancer (PCa) and benign prostatic hyperplasia (BPH). We assessed TGFB1 polymorphisms and their relation to mRNA levels (semi-quantitative RT-PCR) in blood samples as well as the implications in disease occurrence and progression. Peripheral blood samples from 175 patients were analyzed as to 92 BPH and 83 PCa. Samples obtained from 132 healthy males were used as negative controls. PCa patients with a Gleason score greater than 7 presented a higher frequency of the C allele (Leu10Pro). This allele was associated with a higher risk of developing PCa and BPH compared to the population (2.6 and 3.6 times higher, respectively). Patients with TGFB1 transcript levels equal to or more than 70% higher than control levels presented a 5.34 and 2.14-fold higher risk of having PCa and BPH, respectively, relative to the population. No association was detected between polymorphisms and mRNA levels. The C allele of the Leu10Pro polymorphism may predispose men to a more rapid cancer progression. Additionally, higher mRNA levels in the peripheral blood of PCa patients suggest that tumor cells may be disseminated in the circulation and could be used as a biomarker for extra-capsular invasion. ( view less ) View Full Abstract View Article Details View Coded Data Related Articles Influence of the quality of the finished occlusion on postretention occlusal relapse. Oct 2007 Karina Maria Salvatore de Freitas,Guilherme Janson,Marcos Roberto de Freitas,Arnaldo Pinzan,José Fernando Castanha Henriques,Célia Regina Maio Pinzan-Vercelino INTRODUCTION: In this study, we aimed to evaluate the influence of the quality of the finished occlusion on postretention occlusal stability. METHODS: The sample comprised 87 patients with Class I malocclusion, treated with extraction of the 4 first premolars and edgewise mechanics; they were divid... ( view more )ed into 2 groups, according to the quality of their finished occlusions. Group 1 included 44 subjects (23 boys, 21 girls) with posttreatment peer assessment rating (PAR) scores from 0 to 5. The mean pretreatment age was 13.74 years (SD 2.14). The mean treatment time was 1.92 years (SD 0.57), the mean retention time was 1.75 years (SD 0.96), and the mean time of posttreatment evaluation was 5.17 years (SD 1.82). Group 2 included 43 subjects (22 boys, 21 girls) with posttreatment PAR scores greater than 5. The mean initial age was 13.34 years (SD 1.35). The mean treatment time was 2.20 years (SD 0.66), the mean retention time was 1.77 years (SD 0.78), and the mean posttreatment evaluation was 5.47 years (SD 1.60). The PAR and the Little irregularity indexes were measured on the dental casts at pretreatment, posttreatment, and postretention. Intergroup comparisons were made with independent t tests, and the Pearson correlation coefficient was applied to the PAR score for the whole sample at the times evaluated. RESULTS: Well-finished patients had lower posttreatment and postretention PAR scores and greater changes during the treatment and posttreatment periods than did the poorly finished patients. For the Little irregularity index, the only difference between the groups was at the posttreatment stage; group 1 had a smaller irregularity score than group 2. The correlation coefficients showed that the greater the treatment changes, the smaller the posttreatment PAR score and the greater the relapse. But the higher the posttreatment PAR score, the higher the postretention PAR score. CONCLUSIONS: It was concluded that the greater the quality of the orthodontic finished occlusion, the greater are the treatment changes and the amount of relapse and the better is the occlusal status at the postretention stage in Class I malocclusion treated with 4 premolar extractions. ( view less ) View Full Abstract View Article Details   Related Articles Distribution of biofilm on internal and external surfaces of upper complete dentures: the effect of hygiene instruction. Sep 2007 Helena de Freitas Oliveira Paranhos,Claudia Helena Lovato da Silva,Giovana Cherubini Venezian,Leandro Dorigan Macedo,Raphael Freitas de Souza OBJECTIVES: The purpose of this study was to evaluate biofilm distribution over internal and external surfaces of upper complete dentures. It was also aimed at assessing the effect of oral hygiene instructions before and after home use of a disclosing solution. MATERIALS AND METHODS: The sample con... ( view more )sisted of 29 complete denture wearers whose upper prostheses were evaluated. Surface biofilm was disclosed by means of a 1% neutral red solution and quantified with regard to internal and external surfaces. Oral hygiene information was provided on an individual basis. During the second stage, an amount of disclosing solution was given for domestic use. RESULTS: Internal and external surfaces presented a similar amount of biofilm, which was concentrated over the area of the posterior teeth area, palatal rugae and the internal vestibular incline of the distobuccal flange. This pattern was maintained during the study. However, overall amounts were reduced following denture hygiene information. The use of disclosing solution by subjects at home resulted in a further reduction. CONCLUSIONS: It was concluded that biofilm deposits were similar over assessed surfaces, regardless of the type of procedure but irregular areas presented greater amounts. Oral health instruction was effective in reducing the biofilm, in particular when associated with home use of a disclosing agent. ( view less ) View Full Abstract View Article Details View Coded Data Related Articles Acaricidal activity of an oleoresinous extract from Copaifera reticulata (Leguminosae: Caesalpinioideae) against larvae of the southern cattle tick, Rhipicephalus (Boophilus) microplus (Acari: Ixodidae). Jun 20, 2007 Fernando de Freitas Fernandes,Edméia de Paula Souza Freitas The acaricidal activity of oleoresinous extract (oleoresin) from the copaiba tree, Copaifera reticulata was investigated. Oleoresin was dissolved with dimethylsulfoxide (DMSO) and mixed with distilled water at a rate of 0.4 ml of DMSO to 24.6 ml water. Rhipicephalus (Boophilus) microplus larvae wer... ( view more )e exposed to filter paper envelopes impregnated with different oleoresin concentrations. Four envelopes were impregnated with each tested solution. Thirty larvae between 14 and 21 days old were fasted and placed in each envelope. Bioassays were performed at 27 degrees+/-1 degrees C, RH>or=80% and a photoperiod of 12:12 h. Larval mortality was observed 24 h after treatment. Four replicates for each concentration were evaluated to determine lethal concentrations (LC). Oleoresin LC50 and LC99 values were 1579 and 3491 ppm, respectively. The potential use of oleoresin for control of R. (B.) microplus is discussed. The results of this study reinforce the importance of the preservation of C. reticulata in its natural Biome, as a potentially auto-sustainable medicinal resource among the flora of Amazonian forest. ( view less ) View Full Abstract View Article Details View Coded Data Related Articles Study pharmacologic of the GABAergic and glutamatergic drugs on seizures and status epilepticus induced by pilocarpine in adult Wistar rats. Jun 4, 2007 M B Pereira,R L M Freitas,M A G Assis,R F Silva,M M F Fonteles,R M Freitas,R N Takahashi This work was designed to study the influence of drugs during seizures and status epilepticus (SE) induced by pilocarpine and mortality in adult rats. Glutamate (10 and 20 mg/kg), N-methyl-d-aspartate (NMDA, 5 and 10 mg/kg), ketamine (1.5 and 2.0 mg/kg), gabapentin (200 and 250 mg/kg), phenobarbita... ( view more )l (50 and 100 mg/kg) and vigabatrin (250 and 500 mg/kg) were administered intraperitoneally, 30 min prior to pilocarpine (400 mg/kg, i.p.). The animals were observed (24 h) to determine: number of peripheral cholinergic signs, tremors, stereotyped movements, seizures, SE, latency to first seizure and number of deaths after pilocarpine treatment. NMDA and glutamate had pro-convulsive effects in both doses tested. Smaller and higher doses of these drugs no protected and increased pilocarpine-induced seizures and/or mortality. Gabapentin, vigabatrin, phenobarbital and ketamine protected against seizures and increased the latency to first seizure. Thus, these results suggest that caution should be taken in the selection of pharmacotherapy and dosages for patients with seizures and SE because of the possibility of facility the convulsive process toxicity, SE and the mortality of adult animals in this seizures model that is similar temporal lobo epilepsy in humans. ( view less ) View Full Abstract View Article Details   Related Articles Post-poliomyelitis syndrome: case report. Jun 2007 Marco Antonio Orsini Neves,Mariana Pimentel de Mello,Viviane Vieira dos Santos,Osvaldo J M Nascimento,Reny de Souza Antonioli,Gabriel Rodrigues de Freitas,Marcos R G de Freitas The post-polio syndrome (PPS) is an entity characterized for an episode of muscular weakness and/or abnormal muscular fatigue in individuals that had presented acute polio years before. We report the case of PPS in a patient, 40 years, that thirty-five years after had had paralytic poliomyelitis, d... ( view more )eveloped new symptoms of fatigue, muscular atrophy, dyspnea, difficulties in deambulation and muscular and joint pain. The electromyographic findings revealed injuried neurons of the anterior horn of the marrow and reinnervation after muscular tests. ( view less ) View Full Abstract View Article Details View Coded Data Related Articles Benign monomelic amyotrophy with proximal upper limb involvement: case report. Jun 2007 Marco Antonio Orsini Neves,Marcos R G de Freitas,Mariana Pimentel de Mello,Carlos Henrique Dumard,Gabriel R de Freitas,Osvaldo J M Nascimento Monomelic amyotrophy (MA) is a rare condition in which neurogenic amyotrophy is restricted to an upper or lower limb. Usually sporadic, it usually has an insidious onset with a mean evolution of 2 to 4 years following first clinical manifestations, which is, in turned, followed by stabilization. We... ( view more ) report a case of 20-years-old man who presented slowly progressive amyotrophy associated with proximal paresis of the right upper limb, which was followed by clinical stabilization 4 years later. Eletroneuromyography revealed denervation along with myofasciculations in various muscle groups of the right upper limb. We call attention to this rare location of MA, as well as describe some theories concerning its pathophysiology . ( view less ) View Full Abstract View Article Details View Coded Data Related Articles Effect of therapeutic pulsed ultrasound on parameters of oxidative stress in skeletal muscle after injury. May 2007 Luciana S Freitas,Tiago P Freitas,Paulo C Silveira,Luís G Rocha,Ricardo A Pinho,Emilio L Streck Contusion injuries are a very common form of both athletic and non-athletic injury, that effect muscle function. Treatments to augment the normal repair and regeneration processes are important for a wide variety of patients. Therapeutic ultrasound has been claimed to promote tissue repair, especia... ( view more )lly by enhancing cell proliferation and protein synthesis. The present study aimed to investigate the effect of therapeutic pulsed ultrasound (TPU) on parameters of oxidative stress, namely thiobarbituric acid-reactive substances (TBARS), protein carbonyl content and the activities of antioxidant enzymes, catalase and superoxide dismutase (SOD), in skeletal muscle after injury. Wistar rats were submitted to an animal model of muscle (gastrocnemius) laceration. TPU was used once a day. One, three or five days after muscle laceration, the animals were killed by decapitation and oxidative stress parameters were evaluated. Serum CK levels were increased in muscle-injured animals, indicating that the laceration animal model was successful. TBARS were not altered after muscle injury, when compared to the sham group. Protein carbonyl content was increased after muscle laceration. Catalase and SOD activities were increased 1 day after muscle injury and not altered at days 3 and 5. TPU decreased TBARS levels after muscle laceration when compared to injured muscle animals without treatment. Protein carbonyl content evaluation presented similar results. It is tempting to speculate that TPU seems to protect the tissue from oxidative injury. TPU diminished catalase and SOD activities, especially on the first day following muscle laceration. ( view less ) View Full Abstract View Article Details   Related Articles Effects of the vitamin E in catalase activities in hippocampus after status epilepticus induced by pilocarpine in Wistar rats. Apr 18, 2007 D O Barros,S M L Xavier,C O Barbosa,R F Silva,R L M Freitas,F D Maia,A A Oliveira,R M Freitas,R N Takahashi Experimental manipulations suggest that in vivo administration of exogenous antioxidants agents decreases the concentration of free radical in the brain. Neurochemical studies have proposed a role for catalase in brain mechanisms responsible by development to status epilepticus (SE) induced by pilo... ( view more )carpine. The present study was aimed at was investigating the changes in catalase activities after pilocarpine-induced SE. Animals were treated with vitamin E (VIT E) 200 mg/kg (intraperitoneally (i.p.)) and, 30 min later, they received pilocarpine hydrochloride, 400 mg/kg, subcutaneous (s.c.) (P400). Other three groups received VIT E (200 mg/kg, i.p.), pilocarpine (400 mg/kg, s.c.) or 0.9% NaCl (control) alone. Animals were closely observed for behavioral changes, tremors, stereotyped movements, seizures, SE and death, for 24 h following the pilocarpine injection. The brains were dissected after decapitation. The results have shown that pilocarpine administration and resulting SE produced a significant increase in hippocampal catalase activity of (88%). In the group pre-treated which VIT E in hippocampal catalase activity was increase of 67% and 214% when compared with P400 and control group, respectively. Our results demonstrated a direct evidence of an increase in the activity of the hippocampal catalase of rat adults during seizure activity and after the pre-treated which VIT E that could be responsible by regulation of free radical levels during the establishment of SE. ( view less ) View Full Abstract View Article Details   Related Articles Hemodynamic, autonomic and neurohormonal behaviour of familial amyloidotic polyneuropathy and neurally mediated syncope patients during supine and orthostatic stress. Mar 20, 2007 J Freitas,R Santos,E Azevedo,M Carvalho,F Boomsma,A Meiracker,A Falcão de Freitas,C Abreu-Lima Orthostatic intolerance (OI) syndromes are frequent and share symptoms like dizziness and orthostatic syncope. Their pathophysiology however seems to be different. The aim of our work was to evaluate autonomic and hemodynamic behaviour in patients with familial amyloidotic polyneuropathy and neural... ( view more )ly mediated syncope in supine position and after acute orthostatic passive stress. We studied 12 patients with autonomic failure (group A), 12 patients with neurally mediated syncope (group B) and 16 aged matched normal controls (group C), in supine position and during the first 10 min of head-up tilt test (HUTT). Beat-by-beat blood pressure and heart rate were continuously monitored and digitised at 500 Hz. The baroreceptor alfa-index gain (vagal reflex-BRG), high frequency of RR variability (HFRR, vagal tonus) and low frequency of systolic arterial pressure variability (LFSAP, sympathetic tone) were calculated. Catecholamines, plasma brain (BNP) and atrial natriuretic (ANP) peptides were also measured. Hemodynamic data were derived and calculated by the non-invasive modelflow method. During supine position, cardiac output (CO) and stroke volume (SV) were similar in all groups. Mean arterial pressure (MAP) and BNP were higher in group A. Noradrenaline (NOR), BRG, HFRR and LFSAP were extremely low in this group. BRG and adrenaline (ADR) were higher in group B than in controls. Within the first 10 min of HUTT, there was a huge drop of CO, SV and MAP in group A, maintenance of very low levels of neurohormones and lack of autonomic function. HR, LFSAP and ADR had a higher rise at HUTT in group B compared with controls (p<0.01) but a significant decrease of BRG was noted (p<0.05). ANP or BNP did not change with tilt in any group. Different orthostatic intolerance syndromes may show important hormonal, autonomic and hemodynamic differences during supine rest and enhanced after passive orthostatism. ( view less ) View Full Abstract View Article Details   Related Articles Ecosystem approaches and health in Latin America. Feb 2007 Carlos Machado de Freitas,Simone Gomes de Oliveira,Gabriel Eduardo Schütz,Marcelo Bessa Freitas,Mariana Panchita Gómez Camponovo Important environmental changes that have become increasingly pronounced in the last two centuries and that are seriously affecting human health require the development of integrated and participatory scientific approaches that can result in proposals for institutional and public policy changes. Th... ( view more )e purpose of this article is to offer some elements that can contribute to a line of reflection based on studies with ecosystem approaches in the Latin America context. The authors begin with a brief description of current scientific literature in public health that links ecosystems and human health in Latin America; next, they describe and compare the two prevailing trends that form the basis for the theoretical and methodological debates on ecosystem approaches; they also review the empirical research in Latin America or concerning Latin American countries in which an ecosystem approach has been adopted. The results point to limited scientific output on the interface between ecosystems and human health; aspects involving public participation and implementation of institutional changes and public policies are still in a rather incipient stage. ( view less ) View Full Abstract View Article Details   Related Articles Kinesiographic study of deglutition in dentate individuals and complete denture wearers. Jan 2007 Karina Buainain Freitas de Sadalla,Raphael Freitas de Souza,Francisco de Assis Mollo,Marco Antonio Compagnoni Swallowing is used as a clinical method in prosthodontics to determine and record jaw relationships. The aim of this study was to perform a quantitative evaluation, in naturally dentate subjects and complete denture wearers, of three measurements associated with the mandibular position during the a... ( view more )ct of swallowing water: 1. intermaxillary distance on vertical axis; 2. anteroposterior deviation; and 3. lateral deviation. Two groups were selected: Group I (GI) included 40 subjects with complete dentition (mean age 45.27 yrs) and Group II (GII) included 40 bimaxillary edentate subjects, complete denture wearers (mean age 63.92 yrs). A kinesiographic instrument was used for analysis. Three records were taken for each measurement and a mean value obtained. It was concluded that: 1. intermaxillary distance on vertical axis and horizontal deviation were similar for both groups; 2. there was a significant intermaxillary distance on the vertical axis; and 3. for anteroposterior and lateral axis, results showed moderate deviation in relation to maximal intercuspation (MI). ( view less ) View Full Abstract View Article Details   Related Articles Maternal mercury exposure and neuro-motor development in breastfed infants from Porto Velho (Amazon), Brazil. Jan 2007 Rejane Corrêa Marques,José Garrofe Dórea,Wanderley Rodrigues Bastos,Mauro de Freitas Rebelo,Márlon de Freitas Fonseca,Olaf Malm Fish is an important item in the diet of Amazonians, and per se is their best single source of essential nutrients. Rapid urbanization and migration are bringing changes in dietary habits of Amazonians. Exposure to fish-Hg during pregnancy and lactation were studied in 100 women and newborns from P... ( view more )orto Velho. Tissue-Hg concentrations and neurodevelopment (Gesell Developmental Schedules) were assessed at birth and at 6 months in exclusively breastfed infants. Maternal mean frequency of fish consumption was low (<2 meals/week; range 0->7 meals/week) compared to Amazonian standards. Women consuming <2 fish meals/week showed less median hair-Hg (3.5 microgg-1) than women that consumed 2 fish meals/week (5.7 microgg). Median total Hg in maternal hair (5.4 microgg-1) was higher than in newborns (1.6 microgg-1). Significant correlation was observed between maternal hair-Hg and infant hair-Hg at birth (r=0.353; p<0.01) and at six months (r=0.510; p<0.01). Placenta-Hg was also significantly correlated to maternal hair-Hg (r=0.321; p<0.01), newborn hair-Hg (r=0.219; p<0.05), maternal blood-Hg (r=0.250; p<0.01) and to umbilical cord-Hg (r=0.857; p<0.01). Most infants (74%) had normal Gesell Schedules but among the 26% showing neuro-motor development delays only six (7%) had multiple (motor, language, and adaptative) delays. The infants with multiple delays were born from mothers with range of hair-Hg comparable to mothers of normally developed infants. Coincidentally, mothers of infants with multiple delays also showed the lowest range of income and level of education. Fish consumption, income, and level of education varied greatly among these breastfeeding urban mothers. It seems that development delays of exclusively breastfed infants are a component of the health inequalities that accompanies socioeconomic disadvantages. ( view less ) View Full Abstract View Article Details   Related Articles Apolipoprotein E polymorphism in Brazilian dyslipidemic individuals: Ouro Preto study. Jan 2007 A Mendes-Lana,G G Pena,S N Freitas,A A Lima,R L C Nicolato,R M Nascimento-Neto,G L L Machado-Coelho,R N Freitas The influence of apolipoprotein E alleles and genotypes on plasma lipid levels was determined in 185 individuals of mixed ethnicity living in Ouro Preto, Brazil. DNA was obtained from blood samples and the genotypes were determined by an RFLP-PCR procedure. The *3 allele was the most frequent (72%)... ( view more ), followed by *4 (20%) and *2 (8%); *4 frequency was higher and *2 frequency was lower in the dyslipidemic group than in the normal control group. The *2 carriers presented lower LDL and total cholesterol levels compared to the *3 and *4 carriers. All six expected genotypes were observed in the individuals genotyped: E2/2 (2.1%), E4/4 (2.7%), E2/4 (3.7%), E2/3 (8.0%), E3/3 (53.3%), E3/4 (29.9%); no difference in genotype frequencies was found between the normal and dyslipidemic groups. Compared with *2, the presence of *3 increases more than two times the risk for dyslipidemia (OR = 2.31; P = 0.025; 95% CI = 1.06-5.06) and the presence of *4 increases it three times (OR = 3.31; P = 0.006; 95% CI = 1.36-8.04). The only significant effect of genotype was an increased risk for dyslipidemia in the *4 genotype carriers (E3/4 + E4/4) compared with the *2 genotype carriers (E2/2 + E2/3) with OR = 3.69 (95% CI = 1.25-10.88). The present study indicates that in the Ouro Preto admixed population the presence of APOE *2 can confer a protective effect, whereas the presence of APOE *4 implies an enhanced risk for dyslipidemia. ( view less ) View Full Abstract View Article Details   Related Articles Upper and lower pharyngeal airways in subjects with Class I and Class II malocclusions and different growth patterns. Dec 2006 Marcos Roberto de Freitas,Nadyr Maria Penteado Virmond Alcazar,Guilherme Janson,Karina Maria Salvatore de Freitas,José Fernando Castanha Henriques INTRODUCTION: Associations of Class II malocclusions and vertical growth pattern with obstruction of the upper and lower pharyngeal airways and mouth breathing have been suggested. This implies that these malocclusion characteristics have a predisposing anatomical factor for these problems. Therefo... ( view more )re, the purpose of this study was to compare upper and lower pharyngeal widths in patients with untreated Class I and Class II malocclusions and normal and vertical growth patterns. METHODS: The sample comprised 80 subjects divided into 2 groups: 40 Class I and 40 Class II, subdivided according to growth pattern into normal and vertical growers. The upper and lower pharyngeal airways were assessed according to McNamara's airways analysis. The intergroup comparison of the upper and lower airways was performed with 1-way ANOVA and the Tukey test as a second step. RESULTS: The results showed that the upper pharyngeal width in the subjects with Class I and Class II malocclusions and vertical growth patterns was statistically significantly narrower than in the normal growth-pattern groups. CONCLUSIONS: Subjects with Class I and Class II malocclusions and vertical growth patterns have significantly narrower upper pharyngeal airways than those with Class I and Class II malocclusions and normal growth patterns. However, malocclusion type does not influence upper pharyngeal airway width, and malocclusion type and growth pattern do not influence lower pharyngeal airway width. ( view less ) View Full Abstract View Article Details   Related Articles Analysis and estimative of schistosomiasis prevalence for the state of Minas Gerais, Brazil, using multiple regression with social and environmental spatial data. Sep 2006 Ricardo J P S Guimarães,Corina C Freitas,Luciano V Dutra,Ana C M Moura,Ronaldo S Amaral,Sandra C Drummond,Márcio Guerra,Ronaldo G C Scholte,Charles R Freitas,Omar S Carvalho The aim of this work is to establish a relationship between schistosomiasis prevalence and social-environmental variables, in the state of Minas Gerais, Brazil, through multiple linear regression. The final regression model was established, after a variables selection phase, with a set of spatial v... ( view more )ariables which contains the summer minimum temperature, human development index, and vegetation type variables. Based on this model, a schistosomiasis risk map was built for Minas Gerais. ( view less ) View Full Abstract View Article Details View Coded Data Related Articles Alignment stability in Class II malocclusion treated with 2- and 4-premolar extraction protocols. Aug 2006 Guilherme Janson,Mauro Carlos Agner Busato,José Fernando Castanha Henriques,Marcos Roberto de Freitas,Lívia Maria Andrade de Freitas INTRODUCTION: The purpose of this study was to compare the postretention stability of the correction of mandibular anterior-tooth irregularity in patients with Class II malocclusions whose orthodontic treatments included extraction of 2 or 4 premolars. METHODS: A total of 66 patients were selected ... ( view more )who initially had at least one-half-cusp Class II malocclusions. Nineteen patients (9 male, 10 female) with an initial mean age of 14.04 years were treated with extraction of 2 premolars (group 1); 47 patients (20 male, 27 female) with an initial mean age of 13.03 years were treated with extraction of 4 premolars (group 2). A subgroup of group 2, with a similar amount of initial anterior-tooth irregularity as group 1, was also compared with group 1. Little's irregularity index was used to evaluate anterior tooth irregularity in dental casts obtained from each patient before treatment, after treatment, and 5 years after active treatment. Initial cephalometric variables, initial treatment priority index, pretreatment age, treatment time, and posttreatment time of the groups were compared with t tests. Similarly, Little's irregularity index values at prettreament, posttreatment, and postretention were also compared with the t test. Cephalometric treatment changes within groups were evaluated with dependent t tests. RESULTS: There were no statistically significant differences in posttretention anterior-tooth irregularity between groups 1 and 2 or the subgroup. CONCLUSIONS: Treatment of Class II malocclusion with extraction of either 2 maxillary premolars or 4 premolars provides the same mandibular anterior-tooth alignment stability. ( view less ) View Full Abstract View Article Details View Coded Data Related Articles Correlation between mandibular incisor crown morphologic index and postretention stability. Apr 2006 Marcos Roberto de Freitas,Renata Cristina Faria Ribeiro de Castro,Guilherme Janson,Karina Maria Salvatore Freitas,José Fernando Castanha Henriques INTRODUCTION: Considering postretention stability as a result of successful orthodontic treatment, we aimed to verify the influence of mandibular-incisor-crown morphology in the relapse of mandibular anterior crowding. METHODS: The sample comprised 56 white subjects of both sexes with Class I and C... ( view more )lass II malocclusions at pretreatment, treated with extraction of 4 first premolars and edgewise mechanics. No patient underwent interproximal stripping during or after treatment. Mean pretreatment age was 13.23 years. Mean treatment time was 2.11 years, and mean posttreatment evaluation time was 5.12 years. Mandibular anterior crowding was measured with the Little irregularity index, and the mesiodistal and buccolingual proportion of the mandibular incisor crowns was measured with the Peck and Peck index. The measurements were obtained from dental casts at the pretreatment, posttreatment, and postretention stages. The Pearson correlation coefficient was calculated to determine the correlation between mandibular-incisor-crown morphology and the amount of postretention-crowding relapse. RESULTS: The mandibular-incisor-crown morphologic index was not significantly correlated with the amount of mandibular-anterior-crowding relapse. CONCLUSIONS: Mandibular-incisor-crown morphology is not correlated with the amount of mandibular-anterior-crowding relapse. ( view less ) View Full Abstract View Article Details View Coded Data Related Articles Page 1 of 111 1 2 3 4 > Last >> (2764 articles found)

      
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